GLP-1 Daily: Ozempic & Wegovy News

Wegovy Liver-Fat Data at EASD 2026, and What the Wegovy Pill Changes

Monday, October 12, 2026 · 4 min

GLP-1 Daily: Ozempic & Wegovy News cover art

Novo Nordisk's post hoc STEP UP analysis at EASD 2026 says Wegovy brought liver fat below 5 percent in 23 of 26 adults with obesity. We weigh that small, company-presented result and what the oral Wegovy pill does and doesn't change for patients.

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Novo Nordisk's post hoc STEP UP analysis at EASD 2026 says Wegovy brought liver fat below 5 percent in 23 of 26 adults with obesity. We weigh that small, company-presented result and what the oral Wegovy pill does and doesn't change for patients.

In this episode

  1. Wegovy reduced liver fat to normal levels in 9 out of 10 adults with obesity and excess liver fat at EASD2026 - Novo - Medical Update Online — Medical Update Online
    “Novo Nordisk presented post hoc analysis of data from a STEP UP trial sub-population with 55 participants, showing that Wegovy® (pooled semaglutide 7.2 and 2.4 mg) reduced liver fat in adults with obesity without diabetes. Change in percentage of liver fat, determined by…”
  2. Step Back — Now that the FDA has approved an oral version of Wegovy, what actually changes for patients compared with the weekly injection—and what still depends on insurance coverage, prescribing decisions, and longer-term evidence?

    Background sources